Proteases and hormone action
نویسندگان
چکیده
منابع مشابه
Watching proteases in action.
encoding proteases within any genome are easily identified, and three-dimensional structures of many proteases have been solved. Most proteolytic cleavage mechanisms and pro-tease substrate specificities have been established (the latter in some detail) 1. We are also able to block proteolytic activities with potent inhibi-tors. Transgenic approaches have been used for targeted deletions of pro...
متن کاملMechanism of Action of the Thyroid Hormone on the Heart
SUMMARY The foliowing cardiac effects may be attributed to thyroxin: 1-Thyroxin augments all anaerobic processes in the body includ::ng the heart, and decreases the glycogen content of the heart ( 1, 2, 5, 27). The resistance of the heart to anoxia is increased in hyperthyroidism ( 25). 2- Thyroxin influences the cardiac weight and prevents cardiac atrophy (3, 8, 10, 11, 19, 20, 21, 30...
متن کاملUnderstanding parathyroid hormone action.
In addition to regulating serum calcium and stimulating bone resorption, parathyroid hormone (PTH) is known to stimulate bone formation under certain conditions. The mechanisms behind this counterintuitive anabolic action are largely unknown. We have set out to identify PTH-regulated genes that might be responsible for each of these contrasting effects of the hormone. This article describes our...
متن کاملCNS Hormone Action
as a key regulator of whole body homeostasis. In fact, from the respiratory system to the circulatory system, thermoregulation to energy expenditure, the CNS plays a fundamental role in our body’s homeostatic controls. Within the entire CNS, the hypothalamus in particular is generally accepted to mediate the day-to-day regulation of a number of factors including body temperature (42), blood pre...
متن کاملMechanisms of hormone action.
Circulating hormones play an important role in regulating the flux through metabolic pathways. In general, hormones regulate either the activity of key enzymes of metabolism or the activity of protein transport systems such as those found in the plasma membrane and in the inner mitochondrial membrane. Little is known about the mechanism of action of hormones on transport systems, so the discuss...
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ژورنال
عنوان ژورنال: FEBS Letters
سال: 1979
ISSN: 0014-5793
DOI: 10.1016/0014-5793(79)80681-x